Solvent: A Framework for Protein Folding

07/07/2023
by   Jaemyung Lee, et al.
0

Consistency and reliability are crucial for conducting AI research. Many famous research fields, such as object detection, have been compared and validated with solid benchmark frameworks. After AlphaFold2, the protein folding task has entered a new phase, and many methods are proposed based on the component of AlphaFold2. The importance of a unified research framework in protein folding contains implementations and benchmarks to consistently and fairly compare various approaches. To achieve this, we present Solvent, an protein folding framework that supports significant components of state-of-th-arts models in the manner of off-the-shelf interface Solvent contains different models implemented in a unified codebase and supports training and evaluation for defined models on the same dataset. We benchmark well-known algorithms and their components and provide experiments that give helpful insights into the protein structure modeling field. We hope that Solvent will increase the reliability and consistency of proposed models and gives efficiency in both speed and costs, resulting in acceleration on protein folding modeling research. The code is available at https://github.com/kakaobrain/solvent, and the project will continue to be developed.

READ FULL TEXT

page 1

page 2

page 3

page 4

research
06/24/2022

PSP: Million-level Protein Sequence Dataset for Protein Structure Prediction

Proteins are essential component of human life and their structures are ...
research
04/05/2023

EigenFold: Generative Protein Structure Prediction with Diffusion Models

Protein structure prediction has reached revolutionary levels of accurac...
research
06/19/2019

Evaluating Protein Transfer Learning with TAPE

Protein modeling is an increasingly popular area of machine learning res...
research
01/12/2022

Design and Development of PCN-Miner: A tool for the Analysis of Protein Contact Networks

Protein Contact Network (PCN) is a powerful tool for analysing the struc...
research
10/16/2021

DIPS-Plus: The Enhanced Database of Interacting Protein Structures for Interface Prediction

How and where proteins interface with one another can ultimately impact ...
research
06/17/2019

MMDetection: Open MMLab Detection Toolbox and Benchmark

We present MMDetection, an object detection toolbox that contains a rich...
research
05/23/2023

SyNDock: N Rigid Protein Docking via Learnable Group Synchronization

The regulation of various cellular processes heavily relies on the prote...

Please sign up or login with your details

Forgot password? Click here to reset