Robust Segmentation of Optic Disc and Cup from Fundus Images Using Deep Neural Networks

by   Aniketh Manjunath, et al.

Optic disc (OD) and optic cup (OC) are regions of prominent clinical interest in a retinal fundus image. They are the primary indicators of a glaucomatous condition. With the advent and success of deep learning for healthcare research, several approaches have been proposed for the segmentation of important features in retinal fundus images. We propose a novel approach for the simultaneous segmentation of the OD and OC using a residual encoder-decoder network (REDNet) based regional convolutional neural network (RCNN). The RED-RCNN is motivated by the Mask RCNN (MRCNN). Performance comparisons with the state-of-the-art techniques and extensive validations on standard publicly available fundus image datasets show that RED-RCNN has superior performance compared with MRCNN. RED-RCNN results in Sensitivity, Specificity, Accuracy, Precision, Dice and Jaccard indices of 95.64 91.65 87.48 two-stage glaucoma severity grading using the cup-to-disc ratio (CDR) computed based on the obtained OD/OC segmentation. The superior segmentation performance of RED-RCNN over MRCNN translates to higher accuracy in glaucoma severity grading.


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