Possibility of early stopping or interim sample size re-estimation lead
...
Clinical trials disruption has always represented a non negligible part ...
The COVID-19 pandemic continues to affect the conduct of clinical trials...
Sequential likelihood ratio testing is found to be most powerful in
sequ...
This manuscript investigates unconditional and conditional-on-stopping
m...
A two-stage adaptive optimal design is an attractive option for increasi...
In this work, we assume that a response variable is explained by several...