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04/21/2022
Backfilling Cohorts in Phase I Dose-Escalation Studies
The use of `backfilling', assigning additional patients to doses deemed ...
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03/30/2022
Dose Finding Studies for Therapies with Late-Onset Safety and Efficacy Outcomes
In Phase I/II dose-finding trials, the objective is to find the Optimal ...
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04/30/2021
Dose Finding Studies for Therapies with Late-Onset Toxicities: A Comparison Study of Designs
An objective of phase I dose-finding trials is to find the maximum toler...
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10/07/2020