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06/09/2023
The Use of Covariate Adjustment in Randomized Controlled Trials: An Overview
There has been a growing interest in covariate adjustment in the analysi...
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06/22/2022
Coping with Information Loss and the Use of Auxiliary Sources of Data: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions
Clinical trials disruption has always represented a non negligible part ...
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02/07/2022
Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions
The COVID-19 pandemic continues to affect the conduct of clinical trials...
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01/30/2022
Combining Covariate Adjustment with Group Sequential and Information Adaptive Designs to Improve Randomized Trial Efficiency
In clinical trials, there is potential to improve precision and reduce t...
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11/30/2021
Ensuring valid inference for hazard ratios after variable selection
The problem of how to best select variables for confounding adjustment f...
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09/04/2020
Efficient, Doubly Robust Estimation of the Effect of Dose Switching for Switchers in a Randomised Clinical Trial
Motivated by a clinical trial conducted by Janssen Pharmaceuticals in wh...
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07/16/2020
Principled Selection of Baseline Covariates to Account for Censoring in Randomized Trials with a Survival Endpoint
The analysis of randomized trials with time-to-event endpoints is nearly...
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05/28/2020
Clinical trials impacted by the COVID-19 pandemic: Adaptive designs to the rescue?
Very recently the new pathogen severe acute respiratory syndrome coronav...
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04/09/2019
